Overview

Linezolid Dosing Strategies in Drug-Resistant TB

Status:
Recruiting
Trial end date:
2024-09-30
Target enrollment:
Participant gender:
Summary
The purpose of the study is to evaluate the efficacy (how well the medicines work) and tolerability (whether participants stop treatment because of side effects from a drug or treatment) of an anti-TB treatment regimen that compares two doses of linezolid (LZD), combined with bedaquiline (BDQ), delamanid (DLM), and clofazimine (CFZ). This study will also measure the level of these medicines in the participants' blood.
Phase:
Phase 2
Details
Lead Sponsor:
National Institute of Allergy and Infectious Diseases (NIAID)
Treatments:
Bedaquiline
Clofazimine
Diarylquinolines
Linezolid