Lidocaine as an Endotracheal Tube (ETT) Cuff Media

• Status: Completed
• Trial end date: 2019-08-01
• Target enrollment: 0
• Participant gender: All

Summary

Researchers will compare the effects of lidocaine versus air, as a way to fill the breathing tube cuff which is gently inflated to hold in place the trachea (airway) during surgery. Air is the traditional method used to inflate the breathing tube cuff. Researchers wish to find if lidocaine works better than air to facilitate tolerance to the breathing tube (decreased coughing, sore throat, hoarseness). They also want to learn more about its effectiveness for this particular surgical intervention.

• Phase: Phase 2
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Mayo Clinic
• Treatments: Lidocaine

Criteria

Patients who meet the inclusion criteria below and are expected to require ventilatory support for a period of less than 5 hours post-operatively in the cardiac ICU will be enrolled.

Inclusion Criteria:

• All patients > 18 years of age (male and female) who will receive general anesthesia for cardiac surgery at St. Mary's Hospital (SMH) in Rochester, Minnesota

• Cardiac surgery includes: single valve repair, myectomy, cabbage, pericardectomy.

• American Society of Anesthesiologists (ASA) physical status I-III

Exclusion Criteria:

• Age < 18 years old at time of surgery

• Patients who are not sent to the cardiac ICU post-operatively

• Patients who are anticipated to have a difficult tracheal intubation

• Patients having risk factors of postoperative aspiration of gastric contents

• Patients who have respiratory disease or recent respiratory tract infection

• > 1 attempt to secure an airway

• Patients undergoing transcatheter aortic valve replacement (TAVR) procedures or any form of "robotic" procedures