Lidocaine VS Hemodynamic, Metabolic and Hormonal Response

• Status: Not yet recruiting
• Trial end date: 2024-03-08
• Target enrollment: 0
• Participant gender: All

Summary

Intravenous lidocaine - a potent local anesthetic with analgesic and anti- inflammatory properties has been shown to be an effective adjunct that reduces intra and postoperative opioid consumption and facilitates pain management in adults. In children population promising but limited evidence is available. The study has been planned to evaluate the efficacy of continuous intravenous infusion of lidocaine in alleviation of hemodynamic reaction to tracheal intubation, as well as metabolic and hormonal response to laparoscopic procedure in children.

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Medical University of Warsaw
• Treatments: Lidocaine

Criteria

Inclusion Criteria:

• ASA physical status class 1E, 2E, 3E;

• Patients undergoing laparoscopic appendectomy.

Exclusion Criteria:

• Allergy to local anesthetics or contraindications for the use of lidocaine;

• ASA physical status class 4E or higher;

• Severe cardiovascular disease;

• Preoperative bradycardia;

• Preoperative atrioventricular block;

• Renal failure;

• Chronic treatment with analgesics;

• Legal guardians' refusal.