Lidocaine Infusion on Optic Nerve Sheath Diameter in Laparoscopic Hysterectomy in Trendelenburg Position

• Status: Not yet recruiting
• Trial end date: 2023-07-30
• Target enrollment: 0
• Participant gender: Female

Summary

We hypothesize that intravenous lidocaine infusion may have beneficial effect to patients undergoing laparoscopic surgeries in Trendelenburg position by preventing ICP elevation.

• Phase: N/A
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Tanta University
• Treatments: Lidocaine

Criteria

Inclusion Criteria:

• Aged between 35 to 65 years

• American society of anesthesiology (ASA) physical status I - II

• Body mass index (BMI) between 18.5 to 28.0 kg/m2

• Scheduled for total laparoscopic hysterectomy taking approximately 2 h with a 30° Trendelenburg position for management of uterine fibroids or refractory dysfunctional uterine bleeding.

Exclusion Criteria:

1. Patients with eye diseases, central nervous system diseases, cardiovascular diseases, cerebrovascular diseases or diabetes.

2. If these events occurred intraoperative:

• Ultrasound scans or measurements failed to clearly show the structure of Optic Nerve Sheath Diameter (ONSD).

• Surgical time less than 1 h.

• Interruption of carbon dioxide (CO2) pneumoperitoneum and Trendelenburg position.

• Peak airway pressure exceeding 35 cm H2O

3. Patients with a history of allergy to lidocaine.