Lidocaine Infusion as a Treatment for Cocaine Relapse and Craving
Status:
Completed
Trial end date:
2016-03-01
Target enrollment:
Participant gender:
Summary
We propose that the systemic administration of lidocaine following the induction of
cue-induced craving, relative to saline plus cue-induced craving or lidocaine without
cue-induced craving, will block the reconsolidation of cue memories. This will lead to a
reduction in cue-induced craving upon repeated testing as well as subsequent cocaine use and
basal craving.
Phase:
Phase 2
Details
Lead Sponsor:
Bryon Adinoff University of Texas Southwestern Medical Center