Levosimendan Versus Dobutamine for Renal Function in Heart Failure
Status:
Completed
Trial end date:
2017-05-01
Target enrollment:
Participant gender:
Summary
Although inotropes have a favorable effect on central hemodynamics in patients with heart
failure, their effect on renal hemodynamics is incompletely defined. The purpose of this
study is to evaluate the efficacy of a 75 min intravenous infusion of levosimendan compared
to a 75 min infusion of dobutamine on renal hemodynamics and function in patients with
chronic heart failure and signs of cardiorenal syndrome. The investigators hypothesis is that
patients treated with levosimendan will show greater increases in renal blood flow and
glomerular filtration rate (GFR) than those treated with dobutamine.