Levosimendan Administration in Neonates With Transposition of the Great Arteries
Status:
Completed
Trial end date:
2011-09-01
Target enrollment:
Participant gender:
Summary
Calcium sensitizer drugs such as Levosimendan may exert anti-ischemic effect in addition to
positive inotropic and anti-stunning effects mediated by the opening of ATP-sensitive
potassium (KATP) channels. The aim of the study is to test the myocardial protection effect
of peri-operative iv infusion of Levosimendan in a cohort of neonates affected by
transposition of the great arteries undergoing surgical correction by arterial switch.