Levofloxacin-Doxycycline for Helicobacter Pylori Eradication in Saudi Arabia
Status:
Completed
Trial end date:
2014-04-01
Target enrollment:
Participant gender:
Summary
Helicobacter pylori (H. pylori) eradication is achieved in 60-80% with first-line therapy.
Different second-line therapeutic options are available. However, the success of second-line
therapy has not been addressed or reported from Saudi Arabia.
Objectives The primary objective was to evaluate the efficacy of the 10-day course of
levofloxacin, doxycycline and esomeprazole in non-responders to first-line therapies for H.
pylori eradication in Saudi Arabia. Secondary objectives included; symptoms response to
treatment, factors associated with eradication of H. pylori and adverse events associated
with the treatment.