Levetiracetam in the Management of Bipolar Depression

• Status: Completed
• Trial end date: 2008-08-01
• Target enrollment: 0
• Participant gender: All

Summary

A 6-week outpatient, double-blind, placebo-controlled, add-on trial to investigate the effects of levetiracetam on depressive symptoms in bipolar depressed patients.

• Phase: N/A
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Yale University
• Collaborator: Stanley Medical Research Institute
• Treatments: Etiracetam; Levetiracetam; Piracetam

Criteria

Inclusion Criteria:

• DSM-IV diagnosis of bipolar disorder

• Presence of a current major depressive episode on the SCID

• Score of 17 or great on the HDRS

• Capable of giving voluntary written consent

Exclusion Criteria:

• Significant current substance dependence/abuse within 3 months preceding the trial

• Active suicidal ideation

• Pregnant/lactating mothers

• Significant medical history