Overview Leucine in Midlife Depression Status: RECRUITING Trial end date: 2029-06-01 Target enrollment: Participant gender: Summary The study aims to investigate the effects of a 6-week leucine challenge on brain chemistry, connectivity, and behavior in people with midlife depression. The researchers will compare the leucine and an active comparator arm (lysine) for 6 weeks.Phase: PHASE2 Details Lead Sponsor: Emory UniversityCollaborator: National Institute of Mental Health (NIMH)Treatments: LeucineLysine