Letrozole or Tamoxifen in Treating Postmenopausal Women With Breast Cancer
Status:
Completed
Trial end date:
2016-06-30
Target enrollment:
Participant gender:
Summary
RATIONALE: Estrogen can stimulate the growth of breast cancer cells. Hormone therapy using
letrozole may fight breast cancer by reducing the production of estrogen. Hormone therapy
using tamoxifen may fight breast cancer by blocking the uptake of estrogen by the tumor
cells. If is not yet known which treatment regimen is most effective for breast cancer.
PURPOSE: Randomized double-blind phase III trial to compare the effectiveness of letrozole
with that of tamoxifen in treating postmenopausal women who have breast cancer that has been
surgically removed.