Letrozole in Induction of Abortion of Anembryonic Pregnancy

• Status: Recruiting
• Trial end date: 2022-05-30
• Target enrollment: 0
• Participant gender: Female

Summary

Some studies suggest the prescription of aromatase inhibitors prior to the use of misoprostol for inducing drug abortion. the aim of the study is to compare the effectiveness of various regimens of letrozole combined with misoprostol versus using misoprostol alone in inducing complete abortion in patients with blighted ovum.

• Phase: N/A
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Cairo University
• Treatments: Alprostadil; Letrozole; Misoprostol

Criteria

Inclusion Criteria:

• first trimester of pregnancy

• pregnancy duration less than 12 weeks based on LMP.

• non-viable fetus (blighted ovum)

Exclusion Criteria:

• No heart disease,

• No asthma

• No History of thromboembolism

• No History of cancer

• No renal failure

• No liver diseases

• History of allergy to misoprostol or letrozole drugs.