Letrozole and Misoprostol for Termination of Pregnancy up to 63 Days' Gestation

• Status: Recruiting
• Trial end date: 2022-02-28
• Target enrollment: 0
• Participant gender: Female

Summary

Study to determine if a user-friendly medical abortion regimen using letrozole and misoprostol is safe and acceptable.

• Phase: Phase 2
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: Gynuity Health Projects
• Treatments: Letrozole; Misoprostol

Criteria

Inclusion Criteria:

• Pregnancy ≤ 63 days gestational age by ultrasound seeking termination of pregnancy

• Pregnancy visible on ultrasound

• Speaks English or Spanish

• Willing and able to return for follow-up appointment

Exclusion Criteria:

• People with gestations > 63 days gestational age

• Confirmed or suspected ectopic pregnancy or undiagnosed adnexal mass

• Pregnancy of unknown location

• IUD or contraceptive implant in place

• History of allergy to letrozole or misoprostol

• Unable to return for clinic-based follow-up

• Currently breastfeeding

• Twin or multiple pregnancy

• History of liver disease or abnormal liver function