Letrozole, Anastrozole, Exemestane, or Tamoxifen Citrate in Treating Postmenopausal Women With Breast Cancer
Status:
Unknown status
Trial end date:
1969-12-31
Target enrollment:
Participant gender:
Summary
RATIONALE: Estrogen can cause the growth of breast cancer cells. Aromatase inhibitors, such
as letrozole, anastrozole, and exemestane, may fight breast cancer by lowering the amount of
estrogen the body makes. Hormone therapy, using tamoxifen citrate, may fight breast cancer by
blocking the use of estrogen by the tumor cells. It is not yet known whether aromatase
inhibitors or tamoxifen citrate have less effect on memory in patients receiving treatment
for breast cancer.
PURPOSE: This randomized phase III trial is studying letrozole, anastrozole, or exemestane to
see how they effect memory compared with tamoxifen citrate in treating postmenopausal women
with breast cancer.