Lepidium Sativum Extract Versus Simvastatin as an Adjunctive Local Delivery Agents to Non-Surgical Periodontal Therapy
Status:
Completed
Trial end date:
2022-07-01
Target enrollment:
Participant gender:
Summary
The objectives of this clinical study were to:
1. Assess the influence of Lepidium sativum in situ gel versus simvastatin gel on the
clinical parameters in periodontitis patients as the primary objective.
2. Detect the effect of locally delivered Lepidium sativum and simvastatin gels on the
nuclear factor kappa B (NF-κB) level in gingival crevicular fluid as the secondary
objective.