Overview

Lendexal in Patients With Primary Systemic Amyloidosis (AL) Newly Diagnosed

Status:
Completed
Trial end date:
2016-12-01
Target enrollment:
Participant gender:
Summary
Primary outcome measure: - Hematologic response rate to the association of Lenalidomide, Cyclophosphamide and Dexamethasone. Secondary outcome measures: - Organ response rate. - Predictors of response (cardiac biomarkers, serum free light chains). - Toxicity - Safety (type, frequency, severity and relationship of adverse events to the study drug). - Duration of response. - Time to progression. - Overall survival
Phase:
Phase 2
Details
Lead Sponsor:
PETHEMA Foundation
Treatments:
BB 1101
Cyclophosphamide
Dexamethasone
Dexamethasone 21-phosphate
Dexamethasone acetate
Lenalidomide
Thalidomide