Laryngopharyngeal Reflux and Proton Pump Inhibitor (PPI) Treatment
Status:
Completed
Trial end date:
2006-05-01
Target enrollment:
Participant gender:
Summary
This study proposes to investigate prospectively, the presence of molecular markers for
inflammation in laryngopharyngeal reflux (LPR) patients and to study the effect of a proton
pump inhibitor (Aciphex) on these molecular markers.
The investigators will be evaluating a group of patients before and after treatment. This
group will be patients that have untreated laryngopharyngeal reflux diagnosed by
laryngoscopic assessment and a 24-hour probe.