Laryngeal Reflex Study Under Propofol Anesthesia: Effect of Intravenous Lidocaine
Status:
Completed
Trial end date:
2012-05-01
Target enrollment:
Participant gender:
Summary
To describe respiratory and laryngeal responses to laryngeal stimulation during propofol
anesthesia in children. To determine whether the co-administration of lidocaine blunts these
reflex responses. The outcome of primary interest is the reflex laryngospasm.
Hypotheses:
I: The severity of laryngospasm evoked by laryngeal stimulation is reduced 2 min. after iv.
administration on 2mg/kg lidocaine in pediatric patients anesthetized with propofol
(3mcg/ml).
II:The incidence of laryngospasm elicited by controlled stimulation 10min. after iv.
administration of lidocaine is equivalent to the response before the administration of
lidocaine.