Overview

Lapatinib in Combination With Oral Vinorelbine for Metastatic Breast Cancer

Status:
Completed
Trial end date:
2017-07-07
Target enrollment:
Participant gender:
Summary
Phase I part: to determine the recommended dose, and observe the preliminary response and safety profile of the combination of oral lapatinib with vinorelbine in patients with ErbB2 positive metastatic breast cancer. Phase II part: to determine the progression free survival, response rate, and to evaluate the safety profile of the combination of oral lapatinib with vinorelbine in patients with ErbB2 positive metastatic breast cancer. Phase I part has been completed. Phase II part is underway.
Phase:
Phase 1/Phase 2
Details
Lead Sponsor:
National Taiwan University Hospital
Collaborator:
GlaxoSmithKline
Treatments:
Lapatinib
Vinblastine
Vinorelbine