Laparoscopic Assisted Plane Block (LAPB) Trial

• Status: Terminated
• Trial end date: 2021-04-14
• Target enrollment: 0
• Participant gender: All

Summary

This study attempts to demonstrate improvement in analgesia in a more diverse laparoscopic surgery group with the use of laparoscopic assisted transversus abdominis plane blocks. The investigators will compare bupivacaine (treatment arm 1) versus liposomal bupivacaine (treatment arm 2) versus port site injection of local anesthesia with injection of saline placebo (control). The hypothesis is that liposomal bupivacaine will result in improved analgesia when compared to bupivacaine LAPB and control. The investigators further hypothesize that bupivacaine LAPB will be more effective than the control.

• Phase: Phase 4
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: Santa Barbara Cottage Hospital
• Treatments: Bupivacaine

Criteria

Inclusion Criteria:

• Patients aged 18-80 years old

• Patients undergoing non-emergent laparoscopic surgery with planned or continued admission for at least 1 night

• Patients who receive fully laparoscopic procedures including ports up to 15mm, and any blunt dilation of port fascia or sharp extension of skin incisions for specimen extraction.

Exclusion Criteria:

• Patients under 18 or over 80 years old

• Patients who are pregnant

• Patients who are unable to consent themselves

• Patients who undergo an appendectomy for acute appendicitis

• Patients who undergo emergent surgery

• Patients who are converted to open procedure

• Patients who receive concurrent neuraxial anesthesia (spinal, epidural, or indwelling pain pumps)

• Patients who receive concurrent local anesthetic drips planned during or administered immediately after surgery

• Patients who have a contraindication to local anesthetics (e.g. verified allergy, severe hepatic dysfunction)

• Patients who use chronic narcotics