Lantus Effect on Myocardial Glucose Metabolism in T2
Status:
Completed
Trial end date:
2008-06-01
Target enrollment:
Participant gender:
Summary
The primary objective of the present study is to assess changes of myocardial glucose uptake
(MGU) during clamp studies using positron emission tomography (PET) scanning in patients with
type 2 diabetes and idiopathic left ventricular dysfunction (LVD).
The secondary objectives of the study are: assessment of changes of myocardial
microcirculation at rest and during adenosine stimulation using PET; assessment of changes in
myocardial structure and function evaluated by magnetic resonance imaging (MRI); assessment
of glycaemic control by measurement of HbA1c, fasting blood glucose and insulin levels;
assessment of safety (adverse event profile, laboratory data).