Lamotrigine in Reducing Psychologic Side-Effect of Perioperative Ketamine

• Status: Completed
• Trial end date: 2020-12-31
• Target enrollment: 0
• Participant gender: All

Summary

Patient will receive lamotrigine vs. placebo with small sips of water. Lamotrigine reaches peak level 1-4 hours after oral administration.

• Phase: Phase 3
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: The Cleveland Clinic
• Treatments: Anticonvulsants; Ketamine; Lamotrigine

Criteria

Inclusion Criteria:

• 18 -65 Years of age

• Planned overnight hospital stay

Exclusion Criteria:

• Pregnant and planning to become pregnant

• No known History of seizure

• No known History of Schizophrenia

• No known History of unstable angina

• Patients taking Antiepileptic medications

• Known history of Lamotrigine intake in past.

• Any history of allergic reaction to lamotrigine in the past.