Overview Lamotrigine in Reducing Psychologic Side-Effect of Perioperative Ketamine Status: Completed Trial end date: 2020-12-31 Target enrollment: Participant gender: Summary Patient will receive lamotrigine vs. placebo with small sips of water. Lamotrigine reaches peak level 1-4 hours after oral administration. Phase: Phase 3 Details Lead Sponsor: The Cleveland ClinicTreatments: AnticonvulsantsKetamineLamotrigine