Lamotrigine for Symptoms of Geriatric Bipolar Depression
Status:
Completed
Trial end date:
2010-03-01
Target enrollment:
Participant gender:
Summary
This is a 12-week, open label trial of lamotrigine for older adults (age 60 and older) with
type I or type II Bipolar depression. Non-demented older adults with Bipolar I or II
depression, confirmed via the Structured Clinical Interview for the Diagnostic and
Statistical Manual for Mental Disorders (DSM) - Patient edition (SCID-I/P) and meeting
inclusion criteria for depressive symptom severity (score of 18 or greater on the Hamilton
Depression Rating Scale/HAM-D-24) will receive add-on lamotrigine dosed to a target of 200
mg/day.