Lamotrigine Monotherapy in Pediatric Bipolar Disorder
Status:
Completed
Trial end date:
2008-01-01
Target enrollment:
Participant gender:
Summary
There are two purposes for this project. Study 1 is intended to study the safety and efficacy
of Lamotrigine in stabilizing the mood in all phases of pediatric bipolar disorder (Phases:
mixed, manic, hypomanic, or depressed episodes) in 8-17 year old children. These children and
adolescents must be treatment resistant (who failed on two adequate trials of mood
stabilizing medications) to qualify for this study. Study 2 is aimed at examining brain
activity and/or dysfunction before lamotrigine treatment, and to look for any alteration
after lamotrigine treatment. Brain systems associated with attention and emotional processing
will targeted.