Lactobacillus Reuteri for Treatment of Uncomplicated UTI in Pregnant Women

• Status: Completed
• Trial end date: 2019-06-18
• Target enrollment: 0
• Participant gender: Female

Summary

Prevalence of uro-genital infections during pregnancy move between 7% to 12% in developed countries, meanwhile in developing countries this figure moved between 14% and until 55%, such is the case of Mexico. Meanwhile use of antibiotics for 3 to 7 days had established as a standard of care, the use of non-antibiotic therapy, such as cranberry powder or probiotics for prevention/treatment of this conditions is scarce. Randomized controlled trial aimed to evaluate the safety and efficacy of probiotic vs. antibiotics to treat pregnant women with uncomplicated cystitis or asymptomatic bacteriuria

• Phase: N/A
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Innovacion y Desarrollo de Estrategias en Salud
• Collaborator: BioGaia AB
• Treatments: Amoxicillin-Potassium Clavulanate Combination; Anti-Bacterial Agents; Antibiotics, Antitubercular; Clavulanic Acid; Clavulanic Acids; Nitrofurantoin

Criteria

Inclusion Criteria:

• Healthy women on the second or third trimester of pregnancy with positive urine culture according to the operational definition with or without symptoms

• Age 18 to 40 years

• Verbal and Written Informed Consent for participation in the study

Exclusion Criteria:

• Pathologic pregnancy (different for UTI)

• No supplementation of probiotics 2 weeks before study start or during the study period.

• Antibiotic therapy within last 2 weeks before randomization

• Known allergies towards the ingredients of the experimental product

• Inability to comprehend the study protocol

• Systemic diseases

• Multiple pregnancy