Lactobacillus Reuteri DSM 17938 in the Prevention of Antibiotic-associated Diarrhea in Children: Protocol of a Randomized Controlled Trial

• Status: Completed
• Trial end date: 2018-03-01
• Target enrollment: 0
• Participant gender: All

Summary

The aim of this study is to assess the effect of Lactobacillus reuteri DSM 17938 administration for the prevention of diarrhea and AAD in children.

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Medical University of Warsaw
• Treatments: Anti-Bacterial Agents

Criteria

Inclusion Criteria:

• age younger than 18 years;

• oral or intravenous antibiotic therapy which started within 24 hours of enrollment;

• signed informed consent.

Exclusion Criteria:

• pre-existing acute or chronic diarrhea,

• history of chronic gastrointestinal disease (e.g., inflammatory bowel disease, cystic fibrosis, celiac disease, food allergy) or other severe chronic disease (e.g., neoplastic diseases), immunodeficiency,

• use of probiotics within 2 weeks prior to enrollment,

• use of antibiotics within 4 weeks prior to enrollment,

• prematurity, and exclusive breastfeeding.