Lactated Ringer's Solution to Prevent Post-ERCP Pancreatitis
Status:
Not yet recruiting
Trial end date:
2018-08-01
Target enrollment:
Participant gender:
Summary
This is a randomized, double-blinded, controlled trial. This study is a head to head
comparison of normal saline (NS) infusion versus Lactated Ringer's (LR) infusion in patients,
with the primary outcome of post-ERCP pancreatitis occurrence. Patients will be randomized to
either the NS infusion group or the LR infusion group. IVF will be started pre-procedurally
and will be continued throughout the procedure. A IVF bolus will be given at the end of the
procedure and then continued as a continuous infusion. Our null hypothesis is that there will
be no significant difference in the rate of occurrence of post-ERCP pancreatitis between the
infusion of LR and NS solutions. Our alternative hypothesis is that patients receiving LR
solution infusion will experience a decreased rate of post-ERCP pancreatitis compared to
patients receiving NS solution infusion.