Laboratory Aspirin Resistance in Diabetics and Non-Diabetics
Status:
Completed
Trial end date:
2008-06-01
Target enrollment:
Participant gender:
Summary
Despite treatment with aspirin a large number of patients suffer a myocardial infarction. It
has been speculated that these patients might be "resistant" to aspirin, and studies have
indicated that this phenomenon is related to a less favourable prognosis. Furthermore,
patients with diabetes mellitus have an increased risk of myocardial infarction and other
vascular events and, recently, it has been suggested that diabetics do not respond adequately
to aspirin. The purpose of this study is to compare the prevalence of "aspirin resistance" in
diabetics and non-diabetics. Furthermore, patients who suffered a myocardial infarction while
being treated with aspirin are included. We hypothesize that the prevalence of "aspirin
resistance" will be higher among diabetics compared to other patients and to healthy
individuals.