Labor Induction With Misoprostol Versus Oxytocin in Women With Premature Rupture of Membranes

• Status: Unknown status
• Trial end date: 2021-10-01
• Target enrollment: 0
• Participant gender: Female

Summary

This study compares the rate of vaginal delivery after induction of labor with misoprostol versus oxytocin in women with prelabor rupture of membranes. Participants will be randomized to receive either oral misoprotsol every four hours until going into labor, or intravenous oxytocin in increasing dose.

• Phase: N/A
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: sammour.rami
• Treatments: Misoprostol; Oxytocin

Criteria

Inclusion Criteria:

• Women in their 1st - 4th delivery

• Term prelabor rupture of membranes (37+0 to 42+0 gestational age)

• Vertex presentation

• Singleton pregnancy

Exclusion Criteria:

• Multiple pregnancy

• Previous cesarean section

• Chorioamnionitis on admission

• >2 symptomatic uterine contractions in 10 minutes

• Prostaglandins hypersensitivity

• Contraindication for vaginal delivery