Polycystic ovary syndrome (PCOS) is a common endocrine disorder, with a prevalence of 5% to
15% in premenopausal women. Patients with PCOS presents as abnormal menstruation, ovulation
disorders and/or hyperandrogenemia, and often accompanied by insulin resistance and other
metabolic abnormalities. Sleeve gastrectomy was an effective threapy for severe obesity
patients. This study will evaluate the clinical efficacy of sleeve gastrectomy for obese
patients with PCOS. Mealwhile, the specific mechanism of sleeve gastrectomy for improving
obese patients with PCOS will be explored through multi-group analysis.