LOMA: Long-Term Management of Asthma

• Status: Completed
• Trial end date: 2001-09-01
• Target enrollment: 0
• Participant gender: All

Summary

The purpose of this study was to determine whether the use of induced sputum cell counts could guide treatment of asthma more effectively than the use of symptoms and breathing tests. The main outcomes where the time to the first exacerbation and the number of exacerbations.

• Phase: N/A
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Hamilton Health Sciences Corporation
• Collaborator: Canadian Institutes of Health Research (CIHR)

Criteria

Inclusion Criteria:

1. History of asthma for at least one year,confirmed objectively.

2. New or previously reviewed patients where the minimal treatment requirements have not been established within the last six months.

Exclusion Criteria:

1. Smokers or ex-smokers for less than 6 months with a smoking history of more than 10 pack years.

2. Other pulmonary co-morbidity (other than mild or moderate chronic airflow limitation).

3. Subjects having a co-existing illness that precludes them from the study.

4. Inability to give informed consent due to mental or legal reasons.

5. Pregnancy or lactation.

6. Known non-compliance with medications.