LANN-study: Lantus, Amaryl, Novorapid, Novomix Study
Status:
Completed
Trial end date:
1969-12-31
Target enrollment:
Participant gender:
Summary
Many diabetics gain weight while on insulin therapy. In this study, we evaluate the efficacy
of the combination of glimepiride and short-acting insulin on weight control and glucose
control. In this study, 150 diabetics whose diabetic control is inadequate while on maximal
oral treatment will be randomized to either the new combination treatment or twice daily
injections with a mixture of short- and longacting insulin or once-daily injection with a
basal insulin analog. The study will compare glucose control and weight gain during a year
after randomisation between the three treatments.