L-methylfolate Supplementation to OROS-Methylphenidate Pharmacotherapy in ADHD Adults
Status:
Completed
Trial end date:
2017-09-01
Target enrollment:
Participant gender:
Summary
This pilot study seeks to evaluate initial evidence for the effect of L-methylfolate
supplementation to OROS-Methylphenidate pharmacotherapy on ADHD symptoms and associated
features in adults with ADHD, as well as tolerability of this supplementation. The
investigators will conduct a 12-week double-blind randomized placebo-controlled trial with
L-methylfolate supplementing open-label OROS-Methylphenidate (OROS-MPH). The investigators
propose to examine 40 adult (ages 18-55) subjects satisfying the DSM-IV diagnostic criteria
for ADHD.