Overview

L-arginine in Severe Asthma Patients Grouped by Exhaled Nitric Oxide Levels

Status:
Completed
Trial end date:
2019-12-01
Target enrollment:
Participant gender:
Summary
The major impact of this study will be to identify the adult severe asthma cohort that will benefit from supplemental L-arginine therapy. The investigators hypothesize that a subset of adult severe asthma patients will respond to supplemental L-arginine and derive clinical benefit from the addition of this therapy to standard-of-care asthma medications. The investigators hypothesize that the patients that benefit most will have low exhaled nitric oxide concentrations (< 20 ppb) at baseline.
Phase:
Phase 2
Details
Lead Sponsor:
Nicholas Kenyon
University of California, Davis
Collaborator:
National Heart, Lung, and Blood Institute (NHLBI)
Treatments:
Nitric Oxide