L-arginine and Vitamin D Adjunctive Therapy in Pulmonary Tuberculosis (TB)

• Status: Completed
• Trial end date: 2010-05-01
• Target enrollment: 0
• Participant gender: All

Summary

The purpose of this study is to determine whether adjunctive L-arginine and vitamin D can improve response to standard short course TB therapy in people with newly diagnosed pulmonary TB.

• Phase: Phase 3
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Menzies School of Health Research
• Collaborators: Australian National University; National Institute of Health Research and Development, Ministry of Health Republic of Indonesia
• Treatments: Ergocalciferols; Vitamin D; Vitamins

Criteria

Inclusion Criteria:

• Adults >15 years with sputum smear positive pulmonary TB

• New cases only

• Agree to continue treatment in Timika for the full six month course of treatment -Not pregnant

• Consent to enroll in the study.

Exclusion Criteria:

• hypercalcaemia (ionized calcium >1.32 mmol/L) identified at baseline

• taking arginine or vitamin D