The main purpose of this study is to determine the safest maximum dose of an amino acid,
citrulline, which will be used as potential treatment for adult patients with a disorder of
energy metabolism called Mitochondrial Encephalomyopathy, Lactic Acidosis, and Stroke-like
episodes (MELAS). Once established, this dose will be used in a future clinical trial.
Phase:
Phase 1
Details
Lead Sponsor:
Baylor College of Medicine
Collaborators:
Columbia University National Institutes of Health (NIH) University of South Florida