Kuvan Therapy in Phenylketonuria (PKU): The Effect of Blood Phenylalanine Concentration on Kuvan Response
Status:
Completed
Trial end date:
2011-07-19
Target enrollment:
Participant gender:
Summary
The investigators will investigate the effect of blood phenylalanine on Kuvan responsiveness
in the same patients with PKU when their blood phenylalanine concentrations are altered by
diet.
Lowering blood phenylalanine concentrations in Kuvan non-responsive patients with PKU will
increase the frequency of Kuvan responsiveness.