Overview

Kisspeptin to Quantify GnRH Neuronal Function in Health and Disease

Status:
NOT_YET_RECRUITING

Trial end date:
2030-05-01

Target enrollment:

Participant gender:

Summary

The objective of this protocol is to use a case-control paradigm to compare the response to an intravenous administration of kisspeptin in individuals with and without post-covid-19 syndrome. The study subjects will receive a single bolus of kisspeptin. This study will utilize the technique of frequent blood sampling (q10 minutes) to provide detailed neuroendocrine characterization of endogenous LH secretion before and after kisspeptin administration. This frequency of blood sampling is required to define the features of LH pulses.

Phase:

PHASE1

Details

Lead Sponsor:

Stephanie B. Seminara, MD

Collaborator:

Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)