The primary objective is to study the efficacy of botulinum toxin type A (BoNT-A) injected
via kinematic parameters in the treatment of unilateral/bilateral upper extremity tremor in
Parkinson's disease (PD) tremor. Kinematic assessment tools already developed in past
clinical studies will be used in determining injection parameters. The objective is to study
the composition of PD tremor using kinematic tools which may contribute to the knowledge of
tremor complexity and contribute information that would benefit the development of injection
parameters to improve efficacy and optimization of BoNT-A in tremor management. By injecting
all bothersome tremulous upper limbs in Parkinson's disease patients, the investigators
believe a greater improvement in Quality of Life on more daily tasks can be achieved compared
to the investigator's earlier study in unilateral injections (REB#101749), which already
showed significant improvement.
Phase:
Phase 2
Details
Lead Sponsor:
Western University, Canada
Treatments:
abobotulinumtoxinA Botulinum Toxins Botulinum Toxins, Type A incobotulinumtoxinA onabotulinumtoxinA