Kidney Damage in Patients With Moderate Fall in eGFR

• Status: Completed
• Trial end date: 2012-11-01
• Target enrollment: 0
• Participant gender: All

Summary

To compare Iopamidol injection 370 and Iodixanol 320 in evaluating Neutrophil Gelatinase-Associated Lipocalin (NGAL) in patients with moderate fall in eGFR

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Bracco Diagnostics, Inc

Criteria

Inclusion Criteria:

• At least 18 years of age and provides informed consent

• Scheduled to undergo percutaneous coronary intervention

• Documented pre-dose Estimated glomerular filtration rate (eGFR) of greater than or equal to 30 mL/min/1.73 m squared and less than or equal to 59 mL/min/1.73 m squared

Exclusion Criteria:

• Pregnant or lactating females

• Severe congestive heart failure

• History of hyperthyroidism;

• Unstable renal function

• Emergency PCI

• History of hypersensitivity to iodinated contrast agents

• Receiving diuretics to prevent acute renal injury