Ketorolac as an Adjuvant Agent for Postoperative Pain Control Following Arthroscopic ACL Surgery

• Status: Recruiting
• Trial end date: 2022-03-31
• Target enrollment: 0
• Participant gender: All

Summary

1. The investigators aim to examine the use of IV and oral ketorolac as an adjunctive agent to the standard of care pain protocol for postoperative pain control following ACL reconstruction surgery.

2. The investigators hypothesize that the use of IV and oral ketorolac in addition to the standard of care pain protocol will reduce postoperative opioid consumption following ACL reconstruction surgery.

• Phase: Phase 3
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: University Hospitals Cleveland Medical Center
• Treatments: Acetaminophen; Acetaminophen, hydrocodone drug combination; Ketorolac; Ketorolac Tromethamine; Oxycodone

Criteria

Inclusion Criteria:

• Patients between 18 and 89 years old

• Patients undergoing primary anterior cruciate ligament (ACL) reconstruction surgery

Exclusion Criteria:

• Patients below age 18 or above age 89

• Illiterate or non-English speaking individuals

• Patients with contraindications to Ketorolac

• History of chronic alcohol or drug abuse

• Chronic use of psychotropic or analgesic drugs

• Known peptic ulcer disease or bleeding diasthesis

• Renal dysfunction (estimated glomerular filtration rate < 50 mL/min/1.73m2)

• Breastfeeding women

• Pregnant women