Ketorolac and Pregabalin Effects on breaSt Cancer (KePreSt)
Status:
Not yet recruiting
Trial end date:
2026-12-01
Target enrollment:
Participant gender:
Summary
Out of all proportion to its short duration, the perioperative period is critical in
determining the long-term outcome of cancer.
To contribute to a better understanding of the neural and inflammatory mechanisms underlying
this issue, we aim to implement a novel intervention based on the preoperative use of
non-steroidal anti-inflammatory drugs (NSAIDs) with or without an anti-epileptic drug.
Our goal is to understand and transform the perioperative window from being a facilitator of
metastatic progression to arresting and/or eliminating residual disease using repurposing
drugs