Ketorolac Versus Triamcinolone Knee Injections for Osteoarthritis
Status:
Completed
Trial end date:
2014-06-01
Target enrollment:
Participant gender:
Summary
Osteoarthritis is a disabling disease of the joint spaces and has a high impact on society
due to the amount of people who are affected by the disease. Nonoperative management is a
mainstay of therapy in most patients. Ketorolac tromethamine and triamcinolone acetonide
intra-articular knee injections will be compared in a prospective, double-blinded, randomized
trial in subjects with knee osteoarthritis. Subjects will be enrolled from the Orthopaedics
Clinic based on inclusion and exclusion criteria. Intra-articular knee injection of ketorolac
tromethamine or triamcinolone acetonide will be performed under ultrasound guidance. Multiple
outcome measures will be performed throughout the six month period of follow-up. The
investigators predict ketorolac tromethamine will have a longer duration of pain relief when
compared to triamcinolone acetonide. The investigators predict there will be no differences
between the two intra-articular knee injections in terms of function using validated scoring
instruments.