Ketamine's Effect Changes the Cortical Electrophysiological Activity Related to Semantic Affective Dimension of Pain

• Status: Completed
• Trial end date: 2017-11-30
• Target enrollment: 0
• Participant gender: Male

Summary

This is a clinical trial that intend to determine the effects of S-ketamine on event-related potentials associated with semantic affective pain-processing

• Phase: Phase 2/Phase 3
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: Hospital de Clinicas de Porto Alegre
• Treatments: Esketamine; Ketamine

Criteria

Inclusion Criteria:

• male healthy subjects with higher education level

Exclusion Criteria:

• do not understand Portuguese language

• obese patients (BMI > 27 kg/m2)

• use of NSAID, steroids, analgesics, anticonvulsant drugs, as well as alpha and beta-blockers

• score ≥ 13 on Beck II Questionnaire

• sleep deprivation in the night before evaluation