Ketamine and Postoperative Depressive Symptom-PASSION
Status:
Completed
Trial end date:
2018-11-20
Target enrollment:
Participant gender:
Summary
Perioperative depression symptom (PDS) is one of the common mental comorbidity, and
influences the clinical outcomes and prognosis. However, there is no rapid acting treatment
to deal with it during the limited hospital stay. This study aims to determine whether
ketamine could improve the depressive symptom of peirioperative patients. It will also
examine the safety for administrating ketamine as an antidepressant intraoperatively.
Meanwhile, it will show if ketamine could improve anxiety, postoperative pain or delirium.
This trial also will bring great concerns on patients with perioperative mental health and
explore the measures to improve their psycho-related prognosis.