Overview

Ketamine Versus Lidocaine Nebulization for Awake Fiberoptic Intubation

Status:
Completed
Trial end date:
2019-07-25
Target enrollment:
0
Participant gender:
All
Summary
This randomized double-blinded study is performed to compare ketamine versus lidocaine for nebulization for awake nasal fiberoptic intubation as regard efficacy and side effects.
Phase:
Phase 4
Accepts Healthy Volunteers?
No
Details
Lead Sponsor:
Ain Shams University
Treatments:
Ketamine
Lidocaine
Criteria
Inclusion Criteria:

- American Society of Anesthesiologists (ASA) physical status I and II of both sexes
with body weight from 60-90 kg, and planned for elective awake nasal fiberoptic
intubation due to expected difficulty in airway management (e.g. limited mouth
opening, trismus, mandibular/ maxillary swellings or tumors, ludwig's angina, or other
indications).

Exclusion Criteria:

- body weight < 60 kg or > 90 kg

- uncooperative, with mental or psychological problems

- known allergy to any of the study drugs

- pregnancy

- hypertension

- cardiac disease

- liver or renal impairment

- epilepsy,

- asthmatic,

- previous bad experience of awake intubation,

- emergency operations or

- coagulation abnormalities