Overview

Ketamine Infusion for Comorbid PTSD and Chronic Pain

Status:
Completed
Trial end date:
2019-06-04
Target enrollment:
Participant gender:
Summary
The purpose of the study is to investigate the effectiveness of low dose IV ketamine infusion in the treatment of patients with PTSD and comorbid chronic pain. Hypothesis: A single ketamine infusion should be associated with significantly greater reduction in core PTSD symptom levels after the treatment and such an effect is not only due to its analgesic properties but also through unknown mechanism of action that maybe related to NMDA/AMPA receptor modulation.
Phase:
Phase 3
Details
Lead Sponsor:
VA Ann Arbor Healthcare System
Collaborator:
University of Michigan
Treatments:
Ketamine
Ketorolac
Ketorolac Tromethamine