Overview

Ketamine-Induced Brain Changes and Their Modulation by Lamotrigine

Status:
Completed
Trial end date:
2020-12-10
Target enrollment:
Participant gender:
Summary
This study is firstly designed to investigate acute and delayed effects of a single dose of ketamine on functional brain changes during emotional and cognitive challenges and at rest. Secondly, it aims to investigate whether functional brain changes after ketamine require increased glutamatergic signaling and will accordingly be modulated after pretreatment with lamotrigine.
Phase:
N/A
Details
Lead Sponsor:
Charite University, Berlin, Germany
Collaborator:
Boehringer Ingelheim
Treatments:
Anticonvulsants
Ketamine
Lamotrigine