Ketamine Frequency Treatment for Major Depressive Disorder
Status:
Withdrawn
Trial end date:
1969-12-31
Target enrollment:
Participant gender:
Summary
Depression is a wide spread illness. Depression contributes most significantly to national
health care costs. While the number and types of treatments used for depression have expanded
over the years, even with an increased range of options, the response rate, defined as the
number of subjects who have a 50% reduction in depressive symptoms, is estimated to be around
65%.
This randomized clinical trial will examine the frequency of treatment with ketamine in
patients with treatment-resistant depression TRD without psychosis. It will compare two modes
of the ketamine treatment; every other day ketamine, versus two active and four placebo
treatments over the period of 12 days.