Ketamine effect on isoflurane anesthesia This study is designed to study the effect of
ketamine on isoflurane anesthesia. As both drugs are hypnotic and are used to cause sleep
during surgery and other painful procedures, it was long believed that the actions of two
drugs add to each other. For example if a man received both drugs, this man will become awake
from anesthesia much later than if this man was given either of them alone.
However recent studies showed that this is not the case and ketamine can cause fast recovery
from hypnotic effects of isoflurane. This was confirmed in animals.
The aim of current study is to investigate if this effect applies for humans, using a state
of art brain monitoring device in wide use nowadays called BIS or bispectral index. This
device can also shed some light on how ketamine can cause, if any, fast recovery from
isoflurane anesthesia. Simply, by studying electrical wave coming from brain to head skin.